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Medications That Deplete Nutrients and How to Minimize the Damage

It’s been nearly 15 years since licensed pharmacist Suzy Cohen wrote her groundbreaking book, Drug Muggers: Which Medications Are Robbing Your Body of Essential Nutrients — and Natural Ways to Restore Them. A member of the Institute of Functional Medicine, the American College for Advancement in Medicine, and the American Association of Anti-Aging Medicine, Cohen effectively focused our attention on over-the-counter and prescription medications that deplete the body of essential nutrients.

In this post, I build on Cohen’s work by highlighting some of today’s common medications associated with nutrient depletion and provide guidance on how to restore the nutrients they are known to affect.

Image Medications That Deplete Nutrients

While it’s important to point out in a post like this one that some over-the-counter and prescription medications can be helpful in treating and managing various illness and relieving symptoms, it’s similarly important to acknowledge that many people don’t realize that some of these same medications can deplete their body of essential vitamins and minerals. The resulting nutrient depletion can lead to a number of health issues, creating a cycle of dependency on more medical interventions that often involve some over-the-counter and prescription medications. Being able to recognize the medications that can rob your body of what it needs to thrive and knowing how to address this issue proactively will help you maintain optimal health while managing your health.

Common Nutrient-Depleting Medications

Many medications are known to deplete nutrients. Most of these are prescription medications, but some are available over the counter, including proton-pump inhibitors (PPIs) — medications used to reduce stomach acid.

Statins (Cholesterol-Lowering Drugs)1

  • Nutrient Depleted: Coenzyme Q10 (CoQ10)
  • Why It Matters: CoQ10 affects energy production in your cells and has properties that protect your heart. A deficiency in CoQ10 can cause fatigue, muscle pain, and even an increased risk of heart failure, so don’t wait for symptoms to develop before acting.
  • What You Can Do: If you are taking a statin, speak to your healthcare provider about supplementing with CoQ10. If your healthcare provider prescribed a statin medication and did not recommend a CoQ10, consider finding a physician who understands the pros and cons of statins and can explore additional options to treat cardiovascular disease and its associated risk factors.

If you experience muscle pain or weakness, work with your healthcare provider to switch to a different statin medication or explore alternative treatments. Here at PPROVOKE Health, we have patients who had experienced weakness for years during which neither the patient nor doctor was aware this was a side effect of a statin medication. As an aside, I can’t imagine ignoring, dismissing, or failing to address a patient’s years-long experience of weakness and fatigue. Weakness and fatigue are not normal and should be treated just as you would treat heart disease. An increase in energy and strength is usually a sign of improved health and fitness.

Proton Pump Inhibitors (PPIs) (Acid Reflux Medications)2

  • Nutrients Depleted: Calcium, Vitamin B12, and Magnesium.
  • Why It Matters: Long-term use of proton pump inhibitors may lead to low magnesium levels, which is associated with muscle cramps, irregular heartbeat, and seizures. Vitamin B12 deficiency can lead to cognitive issues, nerve damage, and anemia . A deficiency in calcium may increase the risk of bone fractures.
  • What You Can Do: If you are taking a proton pump inhibitor such as dexiansoprazole (Dexilant), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), or rabeprazole (Aciphex), the best thing you can do is work to resolve the underlying problem in your digestive tract. At PROVOKE Health, we have been working with patients for many years on resolving gastrointestinal problems using comprehensive diagnostic testing and integrative treatments to get to the root of the problem.

Our approach may include Continue reading…

Is a B12 Deficiency Making You Sick?

By |2023-09-20T16:30:56-04:00September 20th, 2023|Categories: B12 Deficiency|Tags: , , |0 Comments

B12 deficiency can sneak up on you. You’re feeling strong and energetic, thinking clearly, feeling upbeat, and then gradually, maybe over the course of several months or even years, you begin to notice that you’ve lost the pep in your step.

Your mind and memory aren’t as sharp as they once were. Even mildly strenuous physical activity leaves you breathing hard, and instead of feeling pumped up after exercise, you feel exhausted.

What happened?

B12 Deficiency Graphic

Without a thorough workup, complete with analysis of targeted lab tests, you’ll never know what’s causing you to feel rundown. It could be stress, a lack of (or too much) exercise, a buildup of environmental toxins, or an undiagnosed infection. Or it might be any number of nutritional deficiencies, a combination of those deficiencies, or countless other possible contributing factors.

That’s why I always recommend consulting with a healthcare professional who is attached to a functional medicine practice and obtaining a complete workup and personalized plan of care before starting any treatment, or even taking an over-the-counter supplement. Until you test, you don’t know the root cause of what’s ailing you or what your body may be lacking.

A complete workup often reveals numerous contributing factors and root causes, and one common factor is a vitamin B12 deficiency. Unfortunately, diagnosing and treating B12 deficiency and its underlying cause(s) is more complicated than just ordering a blood test and taking a B12 supplement. In this post, I explain why. But first, it’s important to recognize the symptoms and possible causes of B12 deficiency.

Symptoms of Vitamin B12 Deficiency

Vitamin B12 plays an important role in physiological processes that affect different systems in the body. As a result, symptoms of B12 deficiency can vary considerably, both in symptom type and severity. Here are some common symptoms associated with B12 deficiency:

  • Fatigue and weakness: Feeling unusually tired and weak is one of the most common symptoms of B12 deficiency. This is because B12 is essential for the production of red blood cells, which carry oxygen throughout the body.
  • Anemia: B12 deficiency can lead to a type of anemia called megaloblastic anemia. In this condition, red blood cells are larger and fewer in number, which can result in reduced oxygen-carrying capacity and lead to fatigue, pale skin, and shortness of breath.
  • Nervous system dysfunction: B12 plays a crucial role in maintaining the health of the nervous system. Deficiency can lead to symptoms such as numbness, tingling, or a “pins and needles” sensation in the hands and feet. It can also cause difficulty walking, balance problems, and even affect cognitive functions including memory and concentration.
  • Neuropsychiatric symptoms: B12 deficiency has been associated with mood changes, including depression, anxiety, and irritability. Some individuals may experience more severe neurological symptoms like confusion, memory loss, and even hallucinations in severe cases.
  • Digestive problems: B12 deficiency can lead to digestive issues, such as loss of appetite, weight loss, and constipation.
  • Glossitis and mouth ulcers: Deficiency of B12 can cause inflammation of the tongue (glossitis) and mouth ulcers.
  • Yellowing of the skin: In severe cases, B12 deficiency can affect the liver’s ability to process bilirubin, leading to jaundice and yellowing of the skin and eyes.
  • Heart palpitations and shortness of breath: B12 deficiency can impact the cardiovascular system, leading to palpitations and a rapid heartbeat. Shortness of breath can also occur due to the reduced oxygen-carrying capacity of the blood.
  • Vision changes: Some individuals with B12 deficiency may experience blurred vision or changes in vision.

Recognizing the Causes of B12 Deficiency

Treating vitamin B12 deficiency requires more than just supplementing with B12. I always recommend that you first need to identify and address the root cause of the deficiency. In addition, knowing what’s causing it can help you make better informed decisions about the B12 supplement that’s likely to be most effective. Vitamin B12 deficiency can manifest in several different types, each with distinct causes and characteristics: Continue reading…

Why Am I Always So Tired? Autoimmune Gastritis Could be to Blame

Persistent fatigue is a tough mystery to solve. Causes include anemia, anxiety, depression, infection, cancer, chronic fatigue syndrome (CFS), poor diet, too little or too much exercise, poor sleep, liver or kidney disease, and the list goes on. One of the most overlooked conditions that can cause fatigue is autoimmune gastritis— a chronic inflammatory disease in which the immune system mistakenly destroys parietal cells— cells that produce the stomach acid and intrinsic factor (IF), which the body needs to be able to absorb vitamin B12.

As a result, people with autoimmune gastritis often suffer from pernicious anemia — a condition in which the body is unable to absorb the vitamin B12 needed to manufacture healthy red blood cells. Without sufficient numbers of healthy red blood cells to carry oxygen throughout the body, it is no surprise that people with pernicious anemia suffer persistent fatigue.

When we think about autoimmunity, a few specific conditions come to mind including rheumatoid arthritis (RA), multiple sclerosis (MS), juvenile diabetes, hyperthyroid, and Lupus. Of course, there are others.

What we don’t often consider are the less discussed or less aggressive autoimmune conditions that can have a large impact of how we feel day to day, lead to more progressive illness, and are often associated with the development of additional autoimmune conditions.

Unfortunately, conventional medical doctors often overlook autoimmune gastritis in patients who report chronic fatigue. They may test for anemia and treat it with iron supplements or test for B12 deficiency, see that your B12 level is fine, and never consider whether your body is actually able to absorb and use that B12. Even worse, some people who report fatigue are simply diagnosed as having Continue reading…